Postgraduate Medicine

Editor in Chief: Gurpreet S Wander
  • The emphasis in this book is on providing evidence-based basic understanding of the subject. The pathophysiology of diseases has been simplified. Modes of presentation and approach to investigations are given in a clinically applicable manner. The therapeutic plan, as given in guidelines, is summarized and presented in a way it has to be used in practice.
  • A book for postgraduate students and those practicing medicine after that. Each chapter has been written by an expert in the field.
  • The language is simple to comprehend. The graphs and tables will make it easier for you to have a comprehensive hold on the topic.
  • Effects of COVID-19 on various systems have been included.
  • You will get an Indian perspective of the diseases in each chapter.
  • There are MCQs out of the contents of the chapter for revision. The selected readings can be used for more information on the topic.


Chapter 28, 89, 185, 193 have videos

Table of Contents

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Chapter 1: Practice of Medicine in 21st Century: Opportunities and Challenges
Chapter 2: Good History Taking and General Physical Examination
Chapter 3: Weight Loss, Cachexia, and Fatigue: Clinical Approach and Evaluation
Chapter 4: Abdominal Pain: Evaluation and Management
Chapter 5: Diarrhea and Constipation: Clinical Approach and Management
Chapter 6: Lymphadenopathy: Causes and Evaluation
Chapter 7: Patient with Hepatosplenomegaly: Possibilities and Evaluation
Chapter 8: Ascites: Clinical Approach
Chapter 9: Dyspnea, Syncope and Palpitations: Evaluation
Chapter 10: Cough and Hemoptysis: Evaluation
Chapter 11: Clinical Approach to a Cardiac Murmur
Chapter 12: Patient with Altered Sensorium: Evaluation and Management
Chapter 13: Cutaneous Manifestations and Diseases
Chapter 14: Psychiatric Disorders in Clinical Medicine
Chapter 15: Chest X-ray Evaluation and Some Spotters
Chapter e-15: Chest X-ray Evaluation and Some Spotters
Chapter 16: Nutritional Deficiency Disorders
Chapter 17: Metabolic Disorders: Carbohydrate, Protein, and Others
Chapter 18: Common Metabolic Disorders: Amyloidosis, Porphyria, and Wilson's Disease
Chapter 19: Poisoning and Drug Overdose: General Principles of Management
Chapter 20: Heavy Metal Poisoning
Chapter 21: Genetic Counseling and the Treatment of Genetic Disorders
Chapter 22: Human Leukocyte Antigen System in Molecular and Genetic Medicine
Chapter 23: Electronic Health Records, Artificial Intelligence, and Big Data—Role in Medicine
Chapter e-23: Electronic Health Records, Artificial Intelligence, and Big Data—Role in Medicine
Chapter 24: Psychiatric Disorders: Physicians Perspective
Chapter 25: Palliative and End-of-life Care
Chapter 26: Approach to Older People in Clinical Settings
Chapter 27: Frailty Syndrome
Chapter 28: Falls in Elderly
Chapter 29: Drug Therapy in Elderly
Chapter 30: Infections in Elderly
Chapter 31: Immunology and Vaccination in Elderly
Chapter 32: Cognitive Assessment in Dementia
Chapter 33: Pyrexia of Unknown Origin
Chapter 34: Nosocomial Infection
Chapter 35: Hospital Infection Control
Chapter 36: Principles of Antibiotic Therapy
Chapter 37: Management of Septicemia
Chapter 38: Prevention and Management of Infection in Transplant Recipients
Chapter e-38: Prevention and Management of Infection in Transplant Recipients
Chapter 39: Adult Vaccination
Chapter 40: Infections Caused by Gram-positive Cocci: Streptococcus, Pneumococcus, and Enterococcus
Chapter 41: Staphylococcal Diseases
Chapter 42: Gram-negative Pathogens and Infections
Chapter 43: Gram-negative Bacterial Infections: Salmonellosis, Shigellosis, Brucellosis, Cholera, and Plague
Chapter 44: Tetanus, Botulism, and Other Clostridial Infections
Chapter 45: Influenza Viruses Including H1N1
Chapter 46: RNA Virus Infections
Chapter 47: DNA Viruses: Herpes Simplex, Varicella Zoster, Epstein–Barr Virus, Cytomegalovirus, and Human Papillomavirus
Chapter 48: Other Virus Infections: Chikungunya, Hantavirus, Nipah Virus, and Zika Virus
Chapter e-48: Other Virus Infections: Chikungunya, Hantavirus, Nipah Virus, and Zika Virus
Chapter 49: Rabies
Chapter 50: Dengue Fever
Chapter 51: Human Immunodeficiency Virus Epidemiology and Prevention
Chapter 52: Management of HIV
Chapter 53: Coronaviruses and the Epidemics
Chapter 54: COVID-19: Transmission, Pathophysiology, and Diagnosis
Chapter 55: COVID-19: Clinical Presentation and Management
Chapter 56: Mucormycosis in COVID-19 Pandemic: The New Challenge
Chapter 57: COVID-19 Vaccines
Chapter 58: Tropical Fever: Diagnosis and Management
Chapter 59: Malaria
Chapter 60: Other Protozoal Infections: Leishmaniasis, Toxoplasmosis, Trypanosomiasis, Trichomoniasis, Amoebiasis and Giardiasis
Chapter 61: Diseases of Rickettsiae, Mycoplasma, and Chlamydiae
Chapter 61: Diseases of Rickettsiae, Mycoplasma, and Chlamydiae
Chapter 62: Other Mycobacterial Infections: Leprosy and Nontuberculous Mycobacteria
Chapter 63: Spirochetal Infections: Syphilis, Leptospirosis, and Others
Chapter 64: Common Fungal Infections: Aspergillosis, Candidiasis
Chapter 65: Fungal Infections: Histoplasmosis, Blastomycosis, Pneumocystis Pneumonia, and Others
Chapter 66: Helminthic Infections
Chapter 67: Recognition and Approach to Critically ill Patient
Chapter 68: Monitoring in Intensive Care Unit
Chapter 69: Organization and Quality Indicators in Intensive Care
Chapter 70: Chronic Critical Care
Chapter 71: Fluid Assessment and Management in Critically ill Patients
Chapter 72: Oxygen Therapy
Chapter 73: Mechanical Ventilation: Principles and Strategies
Chapter 74: Acute Respiratory Distress Syndrome
Chapter 75: Approach to Hemodynamic Instability and Shock
Chapter 76: Fever in Intensive Care Unit
Chapter 77: Sepsis and Septic Shock
Chapter 78: Antibiogram and Molecular Diagnostic Tests in an Intensive Care Unit: Interpretation and Relevance
Chapter 79: Antimicrobial Stewardship
Chapter 80: Cytokine Release Syndrome
Chapter 81: Envenomation: Snake and Scorpion
Chapter 82: Cardiopulmonary Resuscitation
Chapter 83: Brain Death: Diagnosis and Management
Chapter 84: End-of-life Care, Medico-legal Aspects, and Ethics in ICU
Chapter 85: Clinical Evaluation of Cardiac Patients
Chapter 86: Epidemiology of Cardiovascular Diseases
Chapter 87: Electrocardiogram
Chapter 88: Noninvasive Cardiac Imaging
Chapter e-88: Noninvasive Cardiac Imaging
Chapter 89: Cardiac Catheterization and Coronary Angiography
Chapter 90: Bradyarrhythmias
Chapter 91: Tachyarrhythmias and Sudden Cardiac Death
Chapter 92: Heart Failure: Pathophysiology and Diagnosis
Chapter 93: Management of Heart Failure
Chapter 94: Acute Rheumatic Fever
Chapter 95: Mitral Valve Disease
Chapter 96: Diseases of the Aortic Valve
Chapter 97: Tricuspid, Pulmonary, and Multivalvular Diseases
Chapter 98: Congenital Heart Disease in the Adults
Chapter 99: Pulmonary Artery Hypertension
Chapter 100: Infective Endocarditis: A Systemic Disease
Chapter 101: Pregnancy and Heart
Chapter 102: Ischemic Heart Disease: Risk Factors and Prevention
Chapter 103: Hypertension: Epidemiology, Presentation, Causes, and Evaluation
Chapter 104: Management of Hypertension
Chapter 105: Dyslipidemias and Drugs Used for Management
Chapter 106: Chronic Stable Angina
Chapter 107: Acute Coronary Syndrome: Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
Chapter 108: Acute ST-elevation Myocardial Infarction
Chapter 109: Diseases of the Myocardium
Chapter 110: Pericardial Diseases
Chapter 111: Diseases of the Aorta
Chapter 112: Peripheral Vascular Disease
Chapter 113: Disorders of the Hypothalamus and Pituitary Gland
Chapter 114: Thyroid Disorders
Chapter 115: Disorders of Adrenal Gland
Chapter 116: Gonadal and Pubertal Disorders
Chapter 117: Obesity
Chapter 118: Endocrine Tumors and Malignancies
Chapter e-118: Endocrine Tumors and Malignancies
Chapter 119: Diabetes Mellitus: Diagnosis, Classification, and Pathophysiology
Chapter 120: Complications of Diabetes
Chapter 121: Diabetes Mellitus: Management
Chapter 122: Calcium and Phosphate Homeostasis
Chapter 123: Parathyroid Disorders
Chapter 124: Diagnosis and Management of Osteoporosis
Chapter 125: Endocrine Disorders in Pregnancy
Chapter 126: Endocrine Disorders of Elderly
Chapter 127: COVID-19 and Endocrine Disorders
Chapter 128: Clinical Approach to Gastrointestinal Diseases
Chapter 129: Esophageal Disorders
Chapter 130: Dyspepsia and Peptic Ulcer Disease
Chapter 131: Nonvariceal Upper Gastrointestinal Bleeding
Chapter 132: Small Bowel Evaluation
Chapter 133: Celiac Disease and Other Causes of Malabsorption
Chapter 134: Intestinal Tuberculosis
Chapter 135: Irritable Bowel Syndrome
Chapter 136: Inflammatory Bowel Disease
Chapter 137: Lower GI Bleed
Chapter 138: Acute Pancreatitis
Chapter 139: Chronic Pancreatitis
Chapter 140: Gallbladder
Chapter 141: Approach to Management of Jaundice: Obstructive Jaundice/Hepatitis
Chapter 142: Acute Liver Failure
Chapter 143: Approach to Management of Chronic Hepatitis
Chapter 144: Treatment of Hepatitis (B, C, and Autoimmune)
Chapter 145: Spectrum of Alcoholic Liver Disease and Management of Alcoholic Hepatitis
Chapter 146: Cirrhosis of Liver and Its Complications
Chapter 147: Nonalcoholic Fatty Liver Disease
Chapter 148: Toxic and Drug-induced Liver Injury
Chapter 149: Hepatocellular Carcinoma
Chapter 150: Liver Transplantation
Chapter 151: Gastrointestinal Manifestations of COVID-19
Chapter 152: Disorders of RBCs: How to Approach?
Chapter 153: Approach to Disorders of Leukocytes
Chapter 154: Bleeding Disorders
Chapter 155: Thrombotic Disorders
Chapter 156: Transfusion Medicine: Principles and Application
Chapter 157: Hematological Malignancies: Classification and Approach
Chapter 158: Cancer: Hallmarks and Prevention
Chapter 159: Cancer Biomarkers: Role and Relevance
Chapter 160: Solid Tumors: An Overview
Chapter 161: Chemotherapy: Principles, Classification, and Toxicity
Chapter 162: Radiotherapy: Principles, Methods, and Application
Chapter 163: Signs, Symptoms and Laboratory Tests of Kidney Disease
Chapter 164: Acute Kidney Injury and Rapidly Progressive Renal Failure
Chapter 165: Acid-base and Electrolytes
Chapter 166: Glomerular Diseases
Chapter 167: Chronic Tubulointerstitial Disorders and Obstructive Nephropathy
Chapter 168: Hypertension, Diabetes, and Kidney Disease
Chapter 169: Infections and Kidney
Chapter 170: Hereditary and Congenital Kidney Diseases
Chapter 171: Systemic Diseases and Kidney
Chapter 172: Pregnancy and Kidneys
Chapter 173: Drugs and Kidneys
Chapter 174: Emerging Renal Syndromes: Onconephrology and Cardiorenal Syndrome
Chapter 175: Uremic Syndrome: Diagnosis and Management
Chapter 176: Preventing Chronic Kidney Disease: In Whom, When, and How?
Chapter 177: Conservative Kidney Care
Chapter 178: Hemodialysis
Chapter 179: Peritoneal Dialysis
Chapter 180: Kidney Transplantation
Chapter 181: COVID-19 and Kidneys
Chapter 182: Neurological Disorders: Basic Considerations and Clinical Approach
Chapter 183: Migraine and Other Headaches
Chapter 184: Raised Intracranial Pressure and Hydrocephalus
Chapter 185: Seizures and Epilepsy
Chapter 186: Acute Ischemic Stroke: A Recent Update
Chapter 187: Hemorrhagic Cerebrovascular Diseases
Chapter 188: Acute Bacterial Meningitis
Chapter 189: Tuberculous Meningitis
Chapter 190: Viral Encephalitis
Chapter 191: Fungal and Parasitic Diseases of the Nervous System
Chapter 192: Demyelinating Diseases of the Central Nervous System
Chapter 193: Movement Disorders: The Clinical Vignette
Chapter 194: Cerebellar Disorders
Chapter 195: Amyotrophic Lateral Sclerosis
Chapter 196: Myelopathies
Chapter 197: Approach to Peripheral Neuropathy
Chapter 198: Guillain–Barré Syndrome
Chapter 199: Myasthenia Gravis
Chapter 200: Disorders of Muscle
Chapter 201: COVID Neurology
Chapter 202: Clinical Approach to Respiratory Problems
Chapter 203: Air Pollution: Health Effects in Current Scenario and Way Forward
Chapter 204: Bronchial Asthma
Chapter 205: Chronic Obstructive Pulmonary Disease
Chapter 206: Occupational Lung Diseases
Chapter 207: Pneumonia and Other Respiratory Infections
Chapter 208: Tuberculosis: Epidemiology, Pathology, and Diagnosis
Chapter 209: Management of Pulmonary Tuberculosis
Chapter 210: Extrapulmonary Tuberculosis
Chapter 211: Nontuberculous Mycobacterial Pulmonary Disease
Chapter 212: Interstitial Lung Diseases
Chapter 213: Bullous Lung Disease
Chapter 214: Sarcoidosis
Chapter 215: Pulmonary Eosinophilic Disorders
Chapter 216: Pulmonary Vasculitides
Chapter 217: Pulmonary Vascular Diseases
Chapter 218: Lung Cancer
Chapter 219: Pleural Diseases
Chapter 220: Mediastinal Anatomy and Disorders
Chapter 221: The Chest Wall
Chapter 222: Respiratory Sleep Disorders
Chapter 223: Respiratory Failure
Chapter 224: Pulmonary Rehabilitation
Chapter 225: COVID-19: Acute Respiratory Manifestations
Chapter 226: Post-COVID Respiratory Complications
Chapter 227: Approach to a Patient with Musculoskeletal Complaints
Chapter 228: Soft Tissue Rheumatism
Chapter 229: Low Back Pain
Chapter 230: Osteoarthritis
Chapter 231: Gout and Other Crystal-related Arthritides
Chapter 232: Rheumatoid Arthritis
Chapter 233: Spondyloarthritis
Chapter 234: Systemic Lupus Erythematosus
Chapter 235: Antiphospholipid Syndrome
Chapter 236: Systemic Sclerosis: An Update
Chapter 237: Sjögren's Syndrome
Chapter 238: Mixed Connective Tissue Disease and Overlap Syndromes
Chapter 239: Idiopathic Inflammatory Myopathies
Chapter 240: Vasculitis
Chapter 241: Miscellaneous Rheumatic Diseases